Articles
A Sound Investment: Auditory Health and Longevity
Contributed by: Annabelle Hutchinson Hearing is one of the most vital senses humans possess, but it is often taken for granted until it begins to fade with age. This article delves into the link between hearing and longevity, shedding light on why prioritizing our...
Did AlphaFold Change the Game for Drug Discovery – and Longevity?
In 2018, Google’s DeepMind made waves when its new neural network AI program, AlphaFold 1, placed first at the Critical Assessment of Structure Prediction (CASP) competition. CASP, a global experiment to refine the methods and models for protein structure prediction,...
Review of Outlive: The Science of Living a Long and Healthy Life” by Peter Attia, M.D.
Contributed by: Annabelle Hutchinson Dr. Peter Attia’s engaging and easy-to-read first book, Outlive, lays out the field of human health and longevity by presenting a comprehensive summary and guide for lifespan (and healthspan) improvement. Famous for his...
Cellular Senescence and Aging: Can We Turn Back the Clock?
Contributed by: Annabelle Hutchinson Cellular Senescence and Aging: Can We Turn Back the Clock? Cellular senescence is a biological process in which cells lose their ability to divide and function correctly. It's an intrinsic component of aging and has been associated...
Optimal Protein Consumption for Longevity
Contributed by: Annabelle Hutchinson When it comes to longevity, one of the first questions people ask is what they should eat. Unfortunately, nutritional epidemiology is plagued by faulty methods of measurement and analysis that lead to biased results, low internal...
EQT Life Sciences Announces €260mm Dementia Fund
Global investment firm EQT Life Sciences announced the close of its €260 million LSP Dementia Fund, outstripping its target fund size of €100 million. EQT is Europe’s largest healthcare buyout firm, with approximately €113.0 billion in assets under management....
Cellular reprogramming and the rise of rejuvenation biotech
Summary: Main takeaway – the future of cellular reprogramming is bright, but there are still major hurdles to overcome before the technology can be used in a clinical setting. Cellular reprogramming is the process of reverting a cell to an earlier state. This paper...
Multi-omic rejuvenation of human cells by maturation phase transient reprogramming
Summary: Main takeaway – continuing partial cellular reprogramming a bit further than most previous attempts seems to result in more substantial rejuvenation. Usually, scientists stop partial reprogramming in the initiation phase, when cells still have not lost their...
How COVID-19 contributes to ageing: a multifaceted view
More than two years have passed since COVID-19 became a global pandemic, and it is still very much a public health issue for everyone. While many countries have loosened control over the disease considering the reduced virulence of the more infectious SARS-CoV2...
Whole-genome sequencing analysis of semi-supercentenarians
Using whole genome sequencing, an international team of scientists have potentially uncovered the secret to how semi-supercentenarians and supercentenarians live so long. The team showed that these individuals had efficient DNA repair mechanisms with reduced...
The effect of environmental stress on ageing in a termite species with low social complexity
Fascinatingly, sociality in invertebrates is associated with longevity and plasticity of the pace of ageing. To reveal more about this phenomenon, Rau and colleges looked at how non-reproducing and reproducing termites responded to environmental stress in the form of...
Gut microbiome pattern reflects healthy ageing and predicts survival in humans
A team in America analysing gut microbiome outputs in blood samples found evidence for a potential link between ageing patterns and microbiome composition in the gut. They identified that healthy ageing in individuals could be partly predicted by a depletion of core...